Various disorders in the work of the heart - the problemmany people. And quite often, in order to eliminate symptoms or suspend the development of the disease, patients are prescribed drugs known as "cardiac glycosides". To this group of medicines belongs and "Korglikon". Instructions for use, indications for treatment, side effects, analogs and reviews are the main issues that patients are interested in. So what is this medicine and what properties does it have?
The preparation "Korglikon" is issued in the form of a transparent solution for injections with a slight yellowish tinge. The medicine is sold in glass ampoules of 1 ml. One package contains 10 ampoules.
The main active substance of the drug isKorglikon - a bioactive glycoside which is obtained from the leaves of lily of the valley. One milliliter of solution contains 600 mg of the component, accordingly, the concentration is 0.06%. As auxiliary substances are present in the composition hlorbutanolgidrat and purified water for injection.
The active components of the preparation are obtained by purifying the extracts of the May lily of the valley and its varieties. This cardiac glycoside, which has a positive inotropic effect on the human body.
This drug activates sodium-calciumexchange membranes of cardiomyocytes, which, in turn, increases the strength of contractions of the heart muscle. On the background of therapy, there is an increase in the shock volume of blood, a decrease in the end systolic and diastolic volume of the heart, and a decrease in myocardial oxygen demand.
Also, the drug provides a negativechronotropic effect. Treatment leads to an increase in the sensitivity of cardiopulmonary baroreceptors, reducing the excessive activity of the sympathetic system. On the other hand, the drug increases the activity of the vagus nerve, it can speed the pulse through the atrioventricular node and, thus, has an antiarrhythmic effect.
In the presence of ciliary tachyarrhythmia, thisthe drug slows the rate of contraction of the ventricles of the heart, lengthens the diastole period, improves the intracardiac hemodynamic. With intravenous administration of the drug begins to act after 3-5 minutes. The maximum effect is observed after 25-30 minutes after taking the medicine.
This drug is often used inmodern medicine. But many patients are interested in the question of in which cases it is advisable to take medication "Korglikon". Indications for use here are different. In particular, it is prescribed to patients suffering from a tachycystolic form of atrial fibrillation. Also, the drug helps with atrial flutter paroxysmal type.
There are other situations in which it is advisableuse the drug "Korglikon." Indications for admission are also attacks of paroxysmal supraventricular tachycardia. In modern medical practice this drug is often prescribed for patients with chronic insufficiency of the second, third and fourth functional class. Naturally, with such a disease, injections are only part of the complex therapy.
Prescribe a similar medicine can only a doctorafter careful diagnosis. The specialist will also determine the most effective dose and schedule the injection. To prepare the solution, the contents of one ampoule are diluted in 10-20 ml of a dextrose or glucose solution with a concentration of 20 or 40%.
A single dose for adult patients is0.5-1 ml of the preparation. Children aged 6 to 12 years, as a rule, receive no more than 0.5-0.75 ml of this drug. A baby of 2 to 5 years of age is prescribed 0.2-0.5 ml. Enter the solution diluted with dextrose intravenously for 5-6 minutes. The procedure is repeated twice a day with a break of at least 8-10 hours. The maximum daily dose for adults is 2 ml of "Korglikona". The duration of therapy is determined individually.
Are all patient categories allowed for treatment withusing the drug "Korglikon"? Instruction for use contains information that contraindications to therapy are still available, so it will be useful to get acquainted with their list:
There are also so-called relativecontraindications, in the presence of which therapy is possible only under constant control. Such conditions include atrioventricular blockade of the first degree, acute myocardial infarction, hypertrophic subaortic stenosis, heart failure with diastolic dysfunction, extrasystole, isolated mitral stenosis, electrolyte level disorders, hypothyroidism, myocarditis, obesity, renal and hepatic insufficiency, alkalosis. With caution, the drug is prescribed for elderly patients.
Many patients before the start of therapy are askedquestions about possible complications against the background of using the medication "Korglikon". The instructions for use contain information that the drug can actually cause side effects. Here is the list of the most common ones:
If there is any deterioration, consult a doctor. Perhaps you just need to adjust the dose. But sometimes a complete withdrawal of the drug is required.
Some patients for one reason or anotherA drug prescribed by a doctor may not be appropriate. What to do in such cases? Is there any way to replace the medicine "Korglikon"? Analogues of this tool in the modern pharmaceutical market are not so easy to find, since drugs with the same active components simply do not exist. Nevertheless, you can try to replace it with drugs with another compound.
For example, approximately the same propertiesmedicinal product "Digoxin". In some cases, as a substitute, you can use the drug "Strophantine", which stands out among others really fast impact. Other analogs include Digitoxin. It is worth noting that all these glycosides are derived from plant material.
Among other factors, for many patientsand the cost of a drug prescribed by doctors is also important. Of course, the exact amount is difficult to determine, because everything depends on the manufacturer, the financial policy of the pharmacy, the city of residence, etc.
So how much will the medicinalmeans "Korglikon"? The packaging price of ten ampoules is about 50-65 rubles. By the way, the drug is sold by prescription. Only the doctor can prescribe to the patient the medicine "Korglikon" (the recipe in Latin looks like this - Corglyconi 0,06%).
In modern medical practice, cardiacglycosides are used quite often. And one of the most popular drugs of this group is "Korglikon". The doctors' testimonies testify that the medicine really copes with its tasks, normalizing the work of the myocardium, eliminating the symptoms of one or another pathology and preventing the development of complications.
Patients also leave positive reviews aboutmedicinal product "Korglikon". The instruction here is extremely simple, the course of treatment does not last long, and the therapy is well tolerated. Despite the possibility of developing some or other adverse reactions, statistical studies indicate that they are extremely rare. And of course, the relatively low cost is one of the advantages of this medication. The disadvantages can be attributed perhaps that not every pharmacy sells this drug, so sometimes it is quite difficult to find.
It is worth noting that in no case should you use this medication alone, as an incorrect dosage can lead to serious intoxication of the body.</ p>>